DNA Repair and Human Disease

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Sommario

Human Premature Aging Disorders and Dysfunction of DNA Repair.- DNA Repair Aspects for RecQ Helicase Disorders.- Trichothiodystrophy.- Roles of the BRCA1 and BRCA2 Breast Cancer Susceptibility Proteins in DNA Repair.- Radiosensitivity of Cells Derived from Down Syndrome Patients.- The Fanconi Anemia/BRCA Pathway.- Is Ataxia Telangiectasia a Result of Impaired Coordination between DNA Repair and Cell Cycle Checkpoint Regulators?.- Mechanisms of DNA Damage and Repair in Alzheimer Disease.- Orchestration of Telomeres and DNA Repair Factors in Mammalian Cells.- Defective Solar Protection in Xeroderma Pigmentosum and Cockayne Syndrome Patients.

Riassunto

DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries.

Dettagli sul prodotto

• Autori: Adayabalam Balajee
• Editore: Springer, Berlin
• Lingue: Inglese
• Formato: Tascabile
• Pubblicazione: 01.01.2014
• EAN: 9781489998996
• ISBN: 978-1-4899-9899-6
• Pagine: 150
• Dimensioni: 155 mm x 9 mm x 235 mm
• Peso: 260 g
• Illustrazioni: XII, 150 p.
• Serie: Medical Intelligence Unit; Medical Intelligence Unit
• Categorie: Scienze naturali, medicina, informatica, tecnica > Medicina > Branche non cliniche; B, Medical microbiology & virology, Human Genetics, Biomedical and Life Sciences, Medical Genetics, Cellular biology (cytology), Medical Microbiology, Cell Biology