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Zusatztext In General this is an excellent book and gives much useful information relating to this distressing condition...A useful feature of this book is the extensive list of references at the end of each chapter...The chapters are well written! the book is well balanced! the illustrations appropriate and the index comprehensive. It is therefore a text which can be recommended to those seeking a greater understanding of the subject. Klappentext Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of this serious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention. Zusammenfassung Amyloidosis is a condition associated with renal dialysis, leading to progressive organ failure, and is of great concern to all clinical nephrologists. This book is aimed at practising nephrologists and will help them successfully to diagnose, relieve, and possibly prevent dialysis-related amyloidosis. Inhaltsverzeichnis Part I: General aspects of amyloidosios 1.: Pathpophysiology of amyloidogenesis 2.: Various clinical types of amyloidosis Part II: Clinical characteristics of *B2=microglobulin amyloidosis 3.: Arthropathy and carpal tunnel syndrome of *B2-microglobulin amyloidosis 4.: Radiology of dialysis amyloidosis 5.: Ultrasonography of the joints 6.: Whole-body scintigraphy Part III: Pathology of *B2-microglobulin deposits 7.: Composition of *B2-microglobulin deposits 8.: Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition Part IV: Physiopathology of *B2-microglobulin accumulation and deposition 9.: Characteristics of *B2-microglobulin metabolism 10.: Involvement of *B2- microglobulin modified with AGEs in dialysis-related amyloidosis 11.: Factors modifying removal and production of *B2-microglobulin 12.: Determinants of fibril precipitation and aggregation in amyloid deposits. Part IV: Review of the clinical evidence on the prophylactic and therapeutic approaches to *B2-microglobulin amyloidosis 13.: Prevention and treatment of *B2-microglobulin amyloidosis ...
