mGLU Receptors

Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes have been identified and classified into three groups based on amino acid sequence similarity, agonist pharmacology, and the signal transduction pathways to which they couple. They perform a variety of functions in the central and peripheral nervous systems, being involved in learning, memory, anxiety, and the perception of pain. They are found in pre- and postsynaptic neurons in synapses of the hippocampus, cerebellum, and cerebral cortex, as well as other parts of the bain and peripheral tissues. This volume will focus on the latest research in the role of Group I mGluRs in health and disease.

Summary

Metabotropic glutamate receptors (mGluRs) are members of the group C family of G-protein-coupled receptors. Eight different mGlu subtypes have been identified and classified into three groups based on amino acid sequence similarity, agonist pharmacology, and the signal transduction pathways to which they couple. They perform a variety of functions in the central and peripheral nervous systems, being involved in learning, memory, anxiety, and the perception of pain. They are found in pre- and postsynaptic neurons in synapses of the hippocampus, cerebellum, and cerebral cortex, as well as other parts of the bain and peripheral tissues. This volume will focus on the latest research in the role of Group I mGluRs in health and disease.

Product details

• Assisted by: Giuseppe Di Giovanni (Editor), Ferdinando Nicoletti (Editor), Richard Teke Ngomba (Editor), Giuseppe Battaglia (Editor), Giusepp Di Giovanni (Editor), Giuseppe Battaglia et al (Editor)
• Publisher: Springer, Berlin
• Content: Book
• Product form: Paperback / Softback
• Publication date: 01.01.2018
• Subject: Natural sciences, medicine, IT, technology > Medicine > Non-clinical medicine
• EAN: 9783319858425
• ISBN: 978-3-31-985842-5
• Pages: 282
• Illustrations: X, 282 p. 28 illus., 26 illus. in color.
• Dimensions (packing): 15.5 x 1.5 x 23.5 cm
• Weight (packing): 450 g
• Series: The Receptors
• Subjects: B, Neuroscience, Neurosciences, Biomedical and Life Sciences, PDZ proteins, excitotoxicity, NMDA receptor, Phospholipase C, postsynaptic