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Bringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, and bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.
About the author
Andreas Hofmann is Associate Professor at the Structural Chemistry Program Leader at Griffith University's Eskitis Institute and an Honorary Senior Research Fellow at the Faculty of Veterinary and Agricultural Sciences at the University of Melbourne. He is also fellow of the Higher Education Academy (UK). Hofmann's research lab focusses on the structure and function of proteins in infectious and neurodegenerative diseases, and also develops computational tools. He is the author of Methods of Molecular Analysis in the Life Sciences (Cambridge, 2014) and Essential Physical Chemistry (2017).Samuel Clokie is the principal bioinformatician at the Birmingham Women's and Children's Hospital, where he leads the implementation of bioinformatic techniques to decipher next generation sequencing data in clinical diagnostics. He is also an Honorary Senior Research Fellow at the Institute of Cancer and Genomic Sciences at the University of Birmingham and before that was a Research Fellow at the National Institutes of Health in Bethesda.
Summary
This best-selling undergraduate textbook introduces the key experimental techniques from across the biosciences. It uniquely integrates the theories and methods driving the fields of biology and medicine, comprehensively covering both the techniques that students will encounter in lab classes and those that underpin recent advances and discoveries.
Report
'After seven editions between 1975 and 2010 this essential textbook has undergone a major update. The new editors, Drs Hofmann and Clokie, recruited many experts to revise individual chapters and added a significant amount of new material, thus making the book even more valuable. This eighth edition is basically a new book that covers the techniques of biochemistry and molecular biology in a very comprehensive manner - it does not go into great detail, but gives the reader a good introduction to all of them. Each chapter contains suggestions for further reading for those in need of a follow-up. Excellent diagrams and illustrations provide help in comprehension of the presented material. Since this text is largely aimed at undergraduate students, it fulfils its role extremely well.' Alexander Wlodawer, National Cancer Institute at Frederick
