Read more
Informationen zum Autor About the EditorsProfessor Anthony Schapira is Professor of Neurological Science and Head of the Department of Clinical Neuroscience at the UCL Institute of Neurology, London, UK and Chairman of Clinical Neurosciences Specialties.Zbigniew Wszolek, MD, is Professor of Neurology in the Department of Neurology, Mayo Clinic, Jacksonville, Florida, USATed M.Dawson, MD, PhD, is Leonard and Madlyn Abramson Professor of Neurodegenerative Diseases and Scientific Director in the Institute for Cell Engineering, Johns Hopkins University, Baltimore, Maryland, USA.Professor Nicholas Wood is Research Director of the UCL Institute of Genetics and Galton Professor of Genetics at UCL National Hospital for Neurology and Neurosurgery, Institute of Neurology, London, UK Klappentext This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject.* Presents a clinically oriented guide to the diseases caused by neurodegeneration* Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually* Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases* Edited by globally leading authorities on the subject, and written by expert contributing authors Zusammenfassung This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject.* Presents a clinically oriented guide to the diseases caused by neurodegeneration* Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually* Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson's Disease, Alzheimer's Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases* Edited by globally leading authorities on the subject, and written by expert contributing authors Inhaltsverzeichnis List of Contributors, viPreface, ixDedication, x1 Pathology of Brain Aging, 1Janna H. Neltner and Peter T. Nelson2 Protein Aggregation and Neurodegeneration: Tauopathies and Synucleinopathies, 12Michel Goedert3 Prion Degeneration, 25James A. Mastrianni4 Excitotoxicity, 37Mark P. Mattson5 Etiology and Pathogenesis of Parkinson Disease, 46Ruth-Mary deSouza and Anthony H.V. Schapira6 Parkinson Disease: Treatment Options - Surgical Therapy, 53Travis S. Tierney and Andres M. Lozano7 Multiple System Atrophy: Clinical, Genetics, and Neuropathology, 58Lucia V. Schottlaender, Anna Sailer, Zeshan Ahmed, Dennis W. Dickson, Henry Houlden, and Owen A. Ross8 Progressive Supranuclear Palsy, 72Huw R. Morris9 Dementia with Lewy Bodies, 83Rodolfo Savica and David S. Knopman10 Corticobasal Degeneration, 93Keith A. Josephs, Jr.11 Alzheimer's Disease, 102Qurat ul Ain Khan and Neill R. Graff-Radford12 Frontotemporal Dementia, 115Christian W. Wider, Barbara Jasinska-Myga, Takuya Konno, and Zbigniew K. Wszolek13 Prion Diseases and Other Rapidly Progressive Dementias, 126Eric Eggenberger and Daniel L. Murman14 Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis, 137Kevin B. Boylan, Mark A. Ross, and Eric J. Sorenson15 Hereditary Spastic Paraplegia, 161Pawel P. Liberski and Craig Blackstone16 Spinal Muscular Atrophy, 179Joseph R. Wooley, Melissa E. Crowder, Noah J. Pyles, and Charlotte J. Sumner17 Spinal and Bulbar Muscular Atrophy (Kennedy Disease), 202Erich Peter Bosch18 Optic Neuropathies, 211Desmond Kidd...
