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Informationen zum Autor Mone Zaidi is the editor of Skeletal Biology and Medicine I: Mechanisms Regulating Bone Mass, Volume 1237, published by Wiley. Klappentext "The volume features current basic, clinical, and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring, including cellular and mechanical triggers, receptors and signaling pathways. Also covered are the effects of other physiological systems and disease states, such as immune system inflammation, diabetes, infection, and cancer on musculoskeletal health. Recent findings are shaping therapeutic directions that focus on both anti-resorptive and anabolic therapies. Basic scientists, clinical investigators, and clinicians with interests spanning endocrinology, physiology, cell biology, pathology, genetics, molecular biology, rheumatology, oncology, and other areas that relate to bone development and homeostasis will find this a valuable resource for the most recent developments in skeletal biology and medicine. This volume presents manuscripts stemming from the 4th New York Skeletal Biology and Medicine Conference, held at Mount Sinai School of Medicine in New York City on April 27-30, 2011. The papers included in this volume include two of the topic areas presented at the conference; the other topic areas are included in Skeletal Biology and Medicine II"--Publisher's description. Zusammenfassung The volume features current basic! clinical! and translational research on aspects of skeletal morphogenesis and remodeling in health and disease. Papers survey vital new insights into the mechanisms of bone development and restructuring! including cellular and mechanical triggers! receptors and signaling pathways. Inhaltsverzeichnis The 2nd Conference on Skeletal Medicine and Biology: Special Features: Mone Zaidi. Historical Reflections and the Future: Iain MacIntyre. Part I: Bone and Blood Vessels:. 1. Oxygen Sensing and Osteogenesis: Ying Wang, Chao Wan, Shawn R. Gilbert, and Thomas L. Clemens. 2. Perspective: The Osteoclast: An Angiogenic Cell?: Frank C. Cackowski and G. David Roodman. 3. Fetal Growth Plate: A Developmental Model of Cellular Adaptation to Hypoxia: Sylvain Provot and Ernestina Schipani. 4. Vascular Bmp-Msx2-Wnt Signaling And Oxidative Stress In Arterial Calcification: Jian-Su Shao, Ziyad Al Aly, Chung-Fang Lai, Su-Li Cheng, Jun Cai, Emily Huang, Abe Behrmann, and Dwight A. Towler. 5. Hypoxia-Mediated Mitochondrial Stress in RAW 264.7 Cells Induces Osteoclast-Like TRAP Positive Cells: Satish Srinivasan, and Narayan G. Avadhani. 6. Stem Cell Therapy in Bone Repair and Regeneration: Neeha Zaidi and Alan J. Nixon. 7. Fluid Shear Stress Up-regulates Vascular Endothelial Growth Factor Gene Expression in Osteoblasts: Mia M. Thi, Dumitru A. Iacobas, Sanda Iacobas, and David C. Spray. Part II: Skeltal Immunity and Inflamation:. 8. B Lymphocytes and the Skeleton: Mark C. Horowitz. 9. Vitamin D in Defense of the Human Immune Response: John S. Adams, Philip T. Liu, Rene Chun, Robert L. Modlin, and Martin Hewison. 10. MRI and Quantification of Draining Lymph Node Function in Inflammatory Arthritis: Steven T. Proulx, Edmund Kwok, Zhigang You, Christopher A. Beck, David J. Shealy, Christopher T. Ritchlin, Brendan F. Boyce, Lianping Xing, and Edward M.Schwarz. 11. Perfusion Abnormalities in Subchondral Bone Associated with Marrow Edema, Osteoarthritis, and Avascular Necrosis: Roy K. Aaron, Jonathan P. Dyke, Deborah McK. Ciombor, Glenn A. Tung. 12. Nuclear Factor of Activated T cell Mediates Proinflamatory Gene Expression in Response to Mechanotransduction: Ayse B. Celil Aydemir, Stephenie Lee, Dae Won Kim, Thomas R. Gardner, Daniel Prince, Jae Mok Ahn, and Francis Young-In Lee. 13. Ort...
