Reaction monitoring by DPPH - M.Pharm. (PharmChem) student Mr. Viraj P. Jatakiya did the project under the guidance of Dr. D.J. Sen & Dr. R.Badmanaban

The project work focuses on the organic reaction monitoring by DPPH on the synthesised eight compounds of two series having variable electronegative atoms X=O/S/NH which have been screened for CNS depression study by synergistic activity by standard drug. This project is a comparison between the SAR study with antioxidant potentiality by DPPH by using logP values with IC50 values with lambda max in UV.The logP value of 4-carboxamido phenyl thio urea (-0.31) is lesser than 2-carboxy phenyl thiourea (1.53) , so the same property arises during potentiality of lmax in UV. The logP value of 4-carboxy phenyl thiourea (0.84) is greater than 2-carboxamido phenyl urea (0.47), so antioxidant potentiality of IC50 value for 2-carboxamido phenyl urea is -661.18 ppm which is more effective than 4-carboxy phenyl thiourea which is 43.79 ppm.

A propos de l'auteur

Der renommierte Akademiker und herausragende Forscher Prof. Dr. Dhrubo Jyoti Sen ist dem Lambert Academic Publishing, Deutschland, für die Veröffentlichung von 13 Büchern dankbar. Das 14. Semester-III am Shri Sarvajanik Pharmacy College, Mehsana, Gujarat, Indien.

Détails du produit

• Auteurs: R Badmanaban, R. Badmanaban, Viraj Jatakiya, Viraj P Jatakiya, Viraj P. Jatakiya, Dhrubo Jyot Sen, Dhrubo Jyoti Sen
• Edition: LAP Lambert Academic Publishing
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 10.01.2012
• EAN: 9783847325413
• ISBN: 978-3-8473-2541-3
• Pages: 80
• Catégorie: Sciences naturelles, médecine, informatique, technique > Médecine > Pharmacie