Receptors - Structure and Function

Klappentext This is a comprehesive review of new methods that can be used for studying cellular receptors and examines how each technique can be used on different receptor types. Zusammenfassung This is a comprehesive review of new methods that can be used for studying cellular receptors and examines how each technique can be used on different receptor types. 1. Probing G protein-coupled receptors by fluorescence spectroscopy; 2. From receptor to endogenous ligand; 3. Point mutations and chimeric receptors in studies of ligand binding domains; 4. Determination of the subunit composition of native and cloned NMDA receptors; 5. Evaluating receptor stoichiometry by fluorescence resonance energy transfer (FRET); 6. Monitoring intracellular trafficking of receptors; 7. Monitoring the turnover kinetics of G protein-coupled receptors; 8. Real time receptor function in vitro: microphysiometry and fluorometric imaging plate reader (FLIPR); 9. Regulation of receptors and receptor-coupled ion channels by protein phosphorylation; 10. Using confocal imaging to measure changes in intracellular ions; 11. Monitoring nuclear receptor function; 12. In vivo gene transfer of antisense to receptors

Détails du produit

• Auteurs: Clare Horton Stanford
• Collaboration: R. W. Horton (Editeur), Roger Horton (Editeur), Roger (Department of Pharmacology Horton (Editeur), Clare Stanford (Editeur), Clare (Department of Pharmacology Stanford (Editeur)
• Edition: Oxford University Press
• Langues: Anglais
• Format d'édition: Livre de poche
• Sortie: 29.11.2001
• EAN: 9780199638826
• ISBN: 978-0-19-963882-6
• Pages: 312
• Thèmes: Practical Approach Series; Practical Approach (Paperback); Practical Approach (Paperback); Practical Approach
• Catégorie: Sciences naturelles, médecine, informatique, technique > Biologie > Général, dictionnaires