Proteases in Health and Disease

Proteases occur naturally in all organisms. They are enzymes that are involved in many physiological reactions such as digestion of food and blood clotting. This volume reviews their role in health and disease and presents the latest research and developments.

Table des matières

1. Membrane-Anchored Serine Proteases in Health and Disease
Toni M. Antalis, Thomas Bugge, and Qingyu Wu
2. Complex Assemblies of Factor IX and X Regulate the Initiation, Maintenance, and Shutdown of Blood Coagulation
Thomas Zögg and Hans Brandstetter
3. Structure and Proteolytic Properties of ADAMTS13, a Metalloprotease Involved in the Pathogenesis of Thrombotic Microangiopathies
Stefano Lancellotti and Raimondo De Cristofaro
4. Thrombin as an Anticoagulant
Enrico Di Cera
5. Regulation of Proteases by Protein Inhibitors of the Serpin Superfamily
Steven T. Olson and Peter G.W. Gettins
6. Multiple Roles of Metalloproteinases in Neurological Disorders
Yi Yang, Jeff W. Hill, and Gary A. Rosenberg

Résumé

Proteases occur naturally in various organisms. They are enzymes which are involved in many physiological reactions such as digestion of food and blood clotting. This title reviews their role in health and disease and presents the research and developments. It discusses discoveries, approaches, and ideas.

Commentaire

PRAISE FOR THE SERIES
"Full of interest not only for the molecular biologist--for whom the numerous references will be invaluable--but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Détails du produit

• Auteurs: Enrico (EDT) Di Cera
• Collaboration: Enrico Di Cera (Editeur), Enrico (Washington University School of Medicine Di Cera (Editeur), Di Cera Enrico (Editeur)
• Edition: Academic Press London
• Langues: Anglais
• Format d'édition: Livre Relié
• Sortie: 01.02.2011
• EAN: 9780123855046
• ISBN: 978-0-12-385504-6
• Pages: 364
• Thèmes: Academic Press; Academic Press; Progress in Molecular Biology; Progress in Molecular Biology and Translational Science
• Catégories: Sciences naturelles, médecine, informatique, technique > Biologie > Biochimie, biophysique; SCIENCE / Life Sciences / Biochemistry, biochemistry, Enzymology