Protein Phosphorylation in Health and Disease

Klappentext This volume explores some of the most exciting recent advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields. Zusammenfassung Explores the advances in basic research on protein phosphorylation in health and disease and how this knowledge is leading to advances in the various fields. Inhaltsverzeichnis Wip1 -dependent signaling pathways in health and diseases Yun-hua Zhu and Dmitry V. Bulavin HijAkt: The PI3k/Akt pathway in virus replication and pathogenesis Ewan F. Dunn and John H. Connor Phosphoproteins in stress-induced disease Lucy E. Dalton, Eleanor Healey, James Irving & Stefan J. Marciniak G-substrate: The Cerebellum and Beyond Shogo Endo Targeting Phosphorylation of Eukaryotic Initiation Factor-2a to Treat Human Disease Melissa J. Fullwood, Wei Zhou and Shirish Shenolikar Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia Jean-Antoine Girault The Role of Protein Phosphorylation in Therapy-resistance and Disease Progression in Chronic Myelogenous Leukemia Wen Chun JUAN and S. Tiong ONG Phosphatases driving mitosis: pushing the gas and lifting the brakes Erika Segear Johnson and Sally Kornbluth Protein tyrosine phosphatases in cancer: Friends and Foes David P. Labbé, Serge Hardy, Michel L. Tremblay Multiple Roles Of Stat3 In Cardiovascular Inflammatory Responses Cheh Peng Lim and Xin-Yuan Fu PAKs in human disease Perry M. Chan and Ed Manser Protein Phosphatases and Alzheimer's Disease Steven P. Braithwaite, Jeffry B. Stock, Paul J. Lombroso, Angus C. Nairn Role of the JNK pathway in human diseases Kanaga Sabapathy Mass spectrometric tools for systematic analysis of protein phosphorylation Nicole St-Denis1 and Anne-Claude Gingras

Table des matières

1. Wip1 -dependent signaling pathways in health and diseases
   Yun-hua Zhu and Dmitry V. Bulavin


2. HijAkt: The PI3k/Akt pathway in virus replication and pathogenesis
   Ewan F. Dunn and John H. Connor


3. Phosphoproteins in stress-induced disease
   Lucy E. Dalton, Eleanor Healey, James Irving & Stefan J. Marciniak


4. G-substrate: The Cerebellum and Beyond
   Shogo Endo


5. Targeting Phosphorylation of Eukaryotic Initiation Factor-2a to Treat Human Disease
   Melissa J. Fullwood, Wei Zhou and Shirish Shenolikar


6. Signaling in striatal neurons: the phosphoproteins of reward, addiction, and dyskinesia
   Jean-Antoine Girault


7. The Role of Protein Phosphorylation in Therapy-resistance and Disease Progression in Chronic Myelogenous Leukemia
   Wen Chun JUAN and S. Tiong ONG


8. Phosphatases driving mitosis: pushing the gas and lifting the brakes
   Erika Segear Johnson and Sally Kornbluth


9. Protein tyrosine phosphatases in cancer: Friends and Foes
   David P. Labbé, Serge Hardy, Michel L. Tremblay


10. Multiple Roles Of Stat3 In Cardiovascular Inflammatory Responses
    Cheh Peng Lim and Xin-Yuan Fu


11. PAKs in human disease
    Perry M. Chan and Ed Manser


12. Protein Phosphatases and Alzheimer's Disease
    Steven P. Braithwaite, Jeffry B. Stock, Paul J. Lombroso, Angus C. Nairn


13. Role of the JNK pathway in human diseases
    Kanaga Sabapathy


14. Mass spectrometric tools for systematic analysis of protein phosphorylation
    Nicole St-Denis1 and Anne-Claude Gingras

Commentaire

Praise for the series:
"Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal

Détails du produit

• Auteurs: Shirish Shenolikar, Shirish (EDT) Shenolikar
• Collaboration: Shirish Shenolikar (Editeur)
• Edition: Academic Press London
• Langues: Anglais
• Format d'édition: Livre Relié
• Sortie: 01.03.2012
• EAN: 9780123964564
• ISBN: 978-0-12-396456-4
• Pages: 458
• Thèmes: Academic Press; Academic Press; Progress in Molecular Biology; Progress in Molecular Biology and Translational Science
• Catégories: Sciences naturelles, médecine, informatique, technique > Biologie > Général, dictionnaires; PHYSIOLOGY, MEDICAL / Physiology