Read more
Zusatztext The Friedel-Crafts acylation reaction is of interest to organic chemists in academia and industry. This work reviews the most important research on the Friedel-Crafts acylation reaction published during the past 30 years! and demonstrates how to make this reaction more economical and less damaging to the environment.-Book News! June 2010The book is well structured and provides the reader with up-to-date references ? New researchers in the field as well as expert industrial practitioners will find valuable insights and up-to-date references here. I would personally recommend this book to all colleagues and graduate-level students who are pursuing research in the field of synthetic manipulation of aromatic compounds! A perfect balance between historical background and new trends toward low-impact environmental strategies can be found throughout the book.-Marco Bandini! Università di Bologna! Journal of the American Chemical Society! Vol. 132 Issue 21-24! 2010 Informationen zum Autor Giovanni Sartori is the Head of the "Clean Synthetic Methodologies Groups" of the University of Parma in Italy. His research interests include all aspects of the heterogeneous catalysis applied to the fine chemicals and pharmaceuticals production with particular attention to the preparation and use of supported organic (chiral) catalysts. Raimondo Maggi is an Associate Professor of Organic Chemistry at the University of Parma. His research interests include the preparation and use of heterogeneous (chiral) catalysts for the environmentally friendly synthesis of fine chemicals and pharmaceuticals. Klappentext The Friedel-Crafts acylation reaction is an electrophilic aromatic substitution that produces aromatic ketones that are used in the synthesis of a wide number of pharmaceuticals and fine chemicals including fragrances! flavors! dyes! and agrochemical products. Written by one of the world's leading authorities in this area of organic chemistry! this volume! the first on Friedel-Crafts in many years! focuses on how to make the reaction more economically and environmentally friendly through the use of green acylating agents! which minimizes the formation of waste. The advantages and disadvantages of homogeneous versus heterogeneous approach is discussed! as is the elusive Fries rearrangement. Zusammenfassung The Friedel-Crafts acylation reaction is a dealkylation process that produces aromatic ketones that are used in the synthesis of a number of pharmaceuticals and fine chemicals. This volume focuses on how to make the reaction economically and environmentally friendly through the use of green acylating agents, which minimizes the formation of waste. Inhaltsverzeichnis Introduction and Scope. Stoichiometric Acylations. Catalytic Homogeneous Acylations. Catalytic Heterogeneous Acylations. Direct Phenol Acylation – Fries Rearrangement. ...
