Transition Metal Catalyzed Transformations of Heteroarenes - Copper and palladium catalyzed arylation and benzylation of 1,3,4-oxadiazoles through C-C bond coupling reaction. DE

This book will give the information about an efficient method for C-H activation of 1,3,4- oxadiazoles using Pd(OAc)2 as a catalyst and Cu(OAc)2 as an oxidant. The method has been applied for direct coupling of these heteroarenes with benzothiazole and aryl boronic acids to prepare their derivatives. The Pd(OAc)2 catalyzed cross-coupling of oxadiazoles and benzothiazole and also the direct arylation of the former with aryl boronic acid have been reported here for the first time and developed a simple, efficient and improved synthesis of 2-aryl and 2-alkenyl 1,3,4-oxadiazoles using CuO nanoparticles as the recyclable catalyst.And also we have developed for the first time an efficient copper catalyzed method for direct benzylation of 1,3,4-oxadiazoles using N-tosylhydrazones. The application of an easily available and less costly catalyst, high yields and rapid conversion are the advantages of the method. The method is a convenient access to various 1,3,4-oxadiazole derivatives.

Product details

• Authors: N Salvanna, N. Salvanna
• Publisher: LAP Lambert Academic Publishing
• Languages: English
• Product format: Paperback / Softback
• Released: 18.05.2025
• EAN: 9786208441463
• ISBN: 9786208441463
• No. of pages: 96
• Subject: Natural sciences, medicine, IT, technology > Chemistry > Organic chemistry