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Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.
In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.
List of contents
1. Introduction: The role of sleep on cardiovascular disease
2. Mitral regurgitation: An overview of pathophysiology and diagnostics
3. Sleep disordered breathing: Phenotypes and challenges in diagnosis
4. The interplay between mitral regurgitation and sleep disordered breathing: Is there a link present?
5. Atrial fibrillation, mitral regurgitation and sleep disordered breathing: Addressing the cofounders
6. Heart failure: Does the management of both pathologies matter?
7. Management of sleep disordered breathing: Effect on Mitral Regurgitation
8. Pharmacotherapy for mitral regurgitation
9. Interventional management of mitral regurgitation: Is there room for SDB improvement?
10. Future Considerations and Conclusions
About the author
Dr. Kyriakos Dimitriadis is an elected Assistant Professor and Interventional Cardiologist at the First Department of Cardiology, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital in Greece. His expertise includes interventional cardiology, hypertension, cardiovascular medicine, blood pressure, atherosclerosis, heart failure, echocardiography, internal medicine, clinical cardiology, myocardial infarction, structural heart disease and atrial fibrillation. Dr. Dimitriadis is also the Chair of the Working Group on “Device-based therapies for the treatment of hypertension” with the European Society of Hypertension. He has a particular research interest in coronary and structural heart interventions, with more than 150 peer reviewed publications in esteemed medical journals.
Konstantinos Tsioufis is Professor of Cardiology and Director of the First Department of Cardiology, University of Athens, Hippokration Hospital, Greece. Professor Tsioufis works as an interventional Cardiologist and Hypertension Specialist. He has special interest in cardiorenal disease, heart failure, hypertension, neuromodulation and peripheral arterial disease. He was a post-doctoral fellow at the Veterans Affairs Medical Centre, at Georgetown University in Washington DC, USA. He has more than 760 publications in peer-reviewed journals, and more than 16000 citations. He was a member of the Task Force for the 2018 ESC/ESH hypertension guidelines, for the 2021 ESC guidelines on CV prevention, and for the 2023 ESH hypertension guidelines. He is currently Vice Dean of the School of Medicine, University of Athens and he has served as President of European Society of Hypertension and President of the Hellenic Society of Cardiology.