Fr. 47.90

Isolation of verbascoside and validation of an analytical method - Method for standardizing the crude extract of the aerial parts of Buddleja stachyoides Cham. & Schltdl. (Scrophulariaceae)

English · Paperback / Softback

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Description

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In this study, the phenylpropanoid verbascoside, identified by NMR, which has pharmacological activities such as antioxidant, analgesic, anti-inflammatory and gastroprotective, was isolated from the ethyl acetate fraction of the aerial parts of Buddleja stachyoides Cham. & Schltdl. The analytical method using high-performance liquid chromatography was developed and validated to quantify the verbascoside content present in the crude alcoholic extract of the aerial parts. It proved to be reliable, sensitive, precise, simple and low-cost, as well as meeting all the validation parameters required by ANVISA's RE No. 899 of May 29, 2003. A long-chain fatty acid, identified as triacontanoic acid, was also isolated from the hexane fraction of B. stachyoides roots. This book is aimed at health professionals and researchers and offers them a contribution to research, development and the production chain of herbal medicines and/or pharmaceutical products based on extracts from B. stachyoides, or any other plant species containing the substance verbascoside.

About the author










Daniella M. S. de Oliveira: regulatory affairs pharmacist at As Ervas Curam Indústria Farmacêutica. From the Federal University of Paraná, she holds a PhD in Pharmaceutical Sciences (2017), a Master's Degree in Pharmaceutical Sciences (2012) and a degree in Pharmacy with a major in Industry (2006).

Product details

Authors Marilis D. Miguel, Obdúlio G. Miguel, Daniella Maria Soares de Oliveira
Publisher Our Knowledge Publishing
 
Languages English
Product format Paperback / Softback
Released 06.03.2024
 
EAN 9786207238231
ISBN 9786207238231
No. of pages 56
Subject Natural sciences, medicine, IT, technology > Medicine > Pharmacy

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