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This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including Cathepsin D, galectins, iron, oxygen, Phospholipase D1, leptin, extracellular vesicles, and more.
Taken alongside its companion volumes, these books update us on what we know about the tumor microenvironment as well as future directions. Tumor Microenvironment: Molecular Players - Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
List of contents
Cathepsin D in the tumor microenvironment of breast and ovarian cancers.- Galectins in the tumor microenvironment: Focus on galectin-1.- Iron in the tumor microenvironment.- Oxygen in the tumor microenvironment: mathematical and numerical modeling.- Roles for Phospholipase D1 in the tumor microenvironment.- Leptin in tumor microenvironment.- The immune consequences of lactate in the tumor microenvironment.- Fatty acid mediators in the tumor microenvironment.- Extracellular Vesicles in the tumor microenvironment: various implications in tumor progression.- Index.
About the author
Alexander Birbrair received his Bachelor's Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette's laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).
Report
"The subject matter tends to be most relevant for the basic and translational science cancer researcher, and would most likely be read by investigators, PhD students, and post-doctoral fellows who work on cancer primarily in a laboratory environment, and less likely by clinicians. ... this book can be very beneficial to basic and translational researchers interested in studying the tumor microenvironment." (George M Rodgers, Doody's Book Reviews, October 9, 2020)
