Read more
This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field -undergraduates, engineers, biologists, medical researchers-will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.
List of contents
1. Acoustofluidic blood component sample preparation and processing in medical applications.- 2. Microfluidic technologies and platforms for protein crystallography.- 3. Application of Sers-based Microfluidics for in Vitro Diagnostics.- 4. Miniaturized Electrochemical Sensors to Facilitate Liquid Biopsy for Detection of Circulating Tumor Markers.- 5. Spiral Inertial Microfluidics for Cell Separation and Biomedical Applications.- 6. Worms on a Chip.- 7. Microfluidic devices for gamete processing and analysis, fertilization and embryo culture and characterization.- 8. Microfluidic organs-on-chips to reconstitute cellular microenvironments.- 9. In vitro tissue construction for organ-on-a-chip applications.- 10. Nanobiodevices for Cancer Diagnostics and Stem Cell Therapeutics.- 11. Nanopore Device for Single-Molecule Sensing Method and Its Application.- 12. Paper Microfluidics for POC Testing in Low-resource Settings.- 13. Paper-Based Microfluidics for Point-of-Care Medical Diagnostics.
About the author
Manabu Tokeshi is a professor in the Division of Applied Chemistry at Hokkaido University. He is also a visiting professor at the ImPACT Research Center for Advanced Nanobiodevices, the Innovative Research Center for Preventive Medical Engineering, and the Institute of Innovation for Future Society at Nagoya University. He received his Ph.D. degree from Kyushu University in 1997. Following his work as a research fellow of the Japan Society of Promotion of Science at The University of Tokyo, he worked at the Kanagawa Academy of Science and Technology as a research staff member (1998-1999), a group subleader (1999-2003), and a group leader (2003-2004). He also served at the Institute of Microchemistry Technology Co. Ltd. as president (2004-2005) and at Nagoya University as an associate professor (2005-2011). In 2011, Dr. Tokeshi was at the Karolinska Institutet in Sweden as a visiting researcher, after which joined Hokkaido University as a professor. His honors include the Outstanding Researcher Award on Chemistry and Micro-Nano Systems from the Society for Chemistry and Micro-Nano Systems (2007), the Pioneers in Miniaturisation Prize from the Lab on a Chip (The Royal Society of Chemistry)/Corning Inc. (2007), and the Masao Horiba Award from HORIBA, Ltd. (2011). His research interests are in the development of micro- and nano-systems for chemical, biochemical, and clinical applications.
Contributors:
Thomas Laurell, Lund University
Manabu Tokeshi, Hokkaido University
Jaebum Choo, Chung-Ang University
Reza M. Mohamadi, University of Toronto
Hou Han Wei, Nanyang Technological University
Han-Sheng Chung, National Cheng Kung University
Severine Le Gac, University of Twente
Yu-suke Torisawa, Kyoto University
Shoji Takeuchi, The University of Tokyo
Yoshinobu Baba, Nagoya University
Masateru Taniguchi, Osaka University
Elain Fu, Oregon State University
Citterio Daniel, Keio University
