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List of contents
1. Steroid Structure and Function from X-Ray Crystallographic Studies W.L. Duax 2. 1H and 13C NMR Spectroscopy of Sterols W.K. Wilson and G.J. Schroepfer, Jr. 3. Theoretical Investigations on Steroid Structure and Quantitative Structure-Activity Relationships M. Bohl 4. Two Approaches to Structure-Activity Relationships in the Field of Sex Steroids and Their Analogs T. Ojasoo, J.C. Dore, J.P. Mornon, and J.P. Raynaud 5. Stilbestrol Estrogens- Molecular/Structural Probes for Understanding Estrogen Action K.S. Korach 6. Aromatase- Mechanism and Inhibition P.A. Cole and C.H. Robinson 7. Structure-Activity Relationships of Glucocorticoids- Importance of the Regulated Gene and Trans-Acting Factors in Determining Glucocorticoid and Antiglucocorticoid Activity S.S. Simons, Jr. 8. Molecular Structure and Biological Activity of Vitamin D Metabolites and Their Analogs N. Ikekawa and S. Ishizuka 9. Molecular Structure and Biological Activity of Brassinolide and Related Brassinosteroids T.Yokota and K. Mori 10. Structure-Activity Relationships of Androgens and Anabolics I. Urbankova, Z. Perina, and O. Hance 11. Structure-Activity Relationships of Steroidal Neuromuscular Blocking Agents Z. Tuba and S. Maho 12. Molecular Biology of Cardiotonic Steroids R. Thomas
About the author
Bohl, Martin
Summary
The indentification of steroid structural features that control particular biological effects is the focus of this book. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book.
