Fr. 188.00

COX-2 Inhibitors

English · Hardback

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Description

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COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

List of contents

The discovery of COX-2.- Structural diversity of selective COX-2 inhibitors.- The molecular and biological basis for COX-2 selectivity.- Pharmacology and toxicology of COX-2 inhibitors.- Efficacy and gastrointestinal safety of selective COX-2 inhibitors.- Role of COX-2 in ulcers and ulcer healing.- COX-2 and the cardiovascular system.- Effects on the kidney: role of COX-2 inhibitors.- Effects on the lungs: role of COX-2 inhibitors.- Reproduction: role of COX-2 and its inhibition.- COX-2 in cancer.

Summary

COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effect. The discovery of COX-2, the evolution of drug development in this field and the implications of these developments in patient therapy are topics of this volume. Animal models and clinical information are presented. The book addresses clinicians interested in the latest information about this class of drugs, researchers and students in t

Product details

Assisted by M. Pairet (Editor), Miche Pairet (Editor), Michel Pairet (Editor), J. van Ryn (Editor), Joanne Van Ryn (Editor), van Ryn (Editor), van Ryn (Editor)
Publisher Springer, Basel
 
Languages English
Product format Hardback
Released 01.01.2004
 
EAN 9783764369019
ISBN 978-3-7643-6901-9
No. of pages 250
Weight 724 g
Illustrations X, 250 p.
Series Milestones in Drug Therapy
Milestones in Drug Therapy
Subject Natural sciences, medicine, IT, technology > Medicine > Pharmacy

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