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In the first years of the existence of this series of monographs, during the so-called "Golden Age" of drug research, the majority of the pa pers published were mainly concerned with the traditional domains of drug research, namely chemistry, pharmacology, toxicology and pre clinical investigations. The series' aim was to give coverage to impor tant areas of research, to introduce new active substances with thera peutic potential and to call attention to unsolved problems. This objective has not changed. The table of contents of the present volume makes evident, however, that the search for new medicines has become increasingly complex, and additional, new disciplines have entered the research arena. The series now includes reviews on bio chemical, biological, immunological, physiological and medicinal aspects of drug research. Researchers actively engaged in the various scientific fields forming the entity of drug research can benefit from the wealth of knowledge and experience of the respective authors, and will be assisted in their endeavour to discover new pharmaceutical agents. Those simply wanting to keep abreast of new developments in the complex, multi-discipline science can turn to the "Progress in Drug Research" volumes as an almost encyclopaedic source of information without having to consult the innumerable original publications. Volume 33 contains 13 reviews, a subject index, an index for the close to 400 articles published in the series so far, and an author and titles index for all 33 volumes.
Inhaltsverzeichnis
Nicotine: an addictive substance or a therapeutic agent?.- Aspirin as an antithrombotic agent.- The mode of action of anti-rheumatic drugs. 1. Anti-inflammatory and immunosuppressive effects of glucocorticoids.- The use of neutrophils, macrophages and organ cultures to assess the penetration of human cells by antimicrobials.- RNA virus evolution and the control of viral disease.- Medicinal agents incorporating the 1,2-diamine functionality.- Adrenergic receptor research: Recent developments.- From podophyllotoxin glucoside to etoposide.- Emerging concepts towards the development of contraceptive agents.- Chemotherapy for systemic mycoses.- Effects of drugs on calmodulin-mediated enzymatic actions.- The significance of DNA technology in medicine.- Immunotherapy for leprosy and tuberculosis.- Index · Sachverzeichnis · Table des matières, Vol. 33.- Index of titles · Verzeichnis der Titel · Index des titres, Vol. 1-33.- Author and paper index · Autoren- und Artikelindex · Index des auteurs et des articles, Vol. 1-33.
